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Mission
The Pharmaceutical Research Center (PRC) is responsible for the safe and ethical provision of investigational/study medications to research subjects enrolled in clinical drug trials within the University of Wisconsin Hospital and Clinics (UWHC) and the UW Carbone Cancer Center (UWCCC).
Contact
- Website Link
- Faculty Leader
Nataliya Uboha - Facility Manager
Susan Johnston
608-263-8863
Facilities
- Facility Statement
Word PDF - Link to Services
- Line Diagram
- Link to UWCCC Acknowledging the Shared Resources Page
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Publications
- McNeel DG, Eickhoff JC, Johnson LE, Roth AR, Perk TG, Fong L, Antonarakis ES, Wargowski E, Jeraj R, Liu G. Phase II Trial of a DNA Vaccine Encoding Prostatic Acid Phosphatase (pTVG-HP [MVI-816]) in Patients With Progressive, Nonmetastatic, Castration-Sensitive Prostate Cancer. J Clin Oncol. 2019 Dec 20;37(36):3507-3517. doi: 10.1200/JCO.19.01701. Epub 2019 Oct 23. PMID: 31644357; PMCID: PMC7194451.
- Wargowski E, Johnson LE, Eickhoff JC, Delmastro L, Staab MJ, Liu G, McNeel DG. Prime-boost vaccination targeting prostatic acid phosphatase (PAP) in patients with metastatic castration-resistant prostate cancer (mCRPC) using Sipuleucel-T and a DNA vaccine. J Immunother Cancer. 2018 Mar 13;6(1):21. doi: 10.1186/s40425-018-0333-y. PMID: 29534736; PMCID: PMC5850960.
- McNeel DG. Therapeutic Cancer Vaccines: How Much Closer Are We? BioDrugs. 2018 Feb;32(1):1-7. doi: 10.1007/s40259-017-0257-y. PMID: 29285731; PMCID: PMC5815920.
- Scarpelli M, Zahm C, Perlman S, McNeel DG, Jeraj R, Liu G. FLT PET/CT imaging of metastatic prostate cancer patients treated with pTVG-HP DNA vaccine and pembrolizumab. J Immunother Cancer. 2019;7(1):23. Epub 20190130. doi: 10.1186/s40425-019-0516-1. PubMed PMID: 30700328; PubMed Central PMCID: PMC6354338.
- Kyriakopoulos CE, Eickhoff JC, Ferrari AC, Schweizer MT, Wargowski E, Olson BM, McNeel DG. Multicenter Phase I Trial of a DNA Vaccine Encoding the Androgen Receptor Ligand-binding Domain (pTVG-AR, MVI-118) in Patients with Metastatic Prostate Cancer. Clin Cancer Res. 2020;26(19):5162-71. Epub 20200608. doi: 10.1158/1078-0432.CCR-20-0945. PubMed PMID: 32513836; PubMed Central PMCID: PMC7541575.