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Mission
The Biomedical Research Model Services Rodent Breeding Core and Research Services Core provides research support across all animal programs on campus. The Breeding Core breeds over 500 strains of mice and rats. Staff commonly breed mice for specific projects, perform studies inside the BRMS core facility, and deliver end point tissues or transfer live mice to laboratories after techniques are performed. Support ranges from a small portion of study to a complete study with final results.
Contact
- Link to Research Cores Directory
- Link to Website
- Email: jody.peter@brms.wisc.edu
- Phone: 608-712-9874
Facilities
- Facility Statement
Word PDF - Link to Services List
- Please contact the core directly for line diagrams.
Acknowledgements Statement:
Please consider acknowledging the University of Wisconsin School of Medicine and Public Health (SMPH) Biomedical Research Model Services (BRMS) Research Services in manuscripts and publications that include any work supported by our professional staff and dedicated space. A sample acknowledgement: “The author(s) thank the University of Wisconsin School of Medicine and Public Health Biomedical Research Model Services shared resource for the use of its facilities and their Research Services team for expertise including breeding and specialized techniques.”
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Publications
- Foster HR, Ho T, Potapenko E, Sdao SM, Huang SM, Lewandowski SL, VanDeusen HR, Davidson SM, Cardone RL, Prentki M, Kibbey RG, Merrins MJ. β-cell deletion of the PKm1 and PKm2 isoforms of pyruvate kinase in mice reveals their essential role as nutrient sensors for the KATP channel. Cell Biology. 2022. doi.org/10.7554/eLife.79422.
- Kohn EM, Taira C, Dobson H, Santos Dias LD, Okaa U, Wiesner DL, Wüthrich M, Klein BS. Variation in Host Resistance to Blastomyces dermatitidis: Potential Use of Genetic Reference Panels and Advances in Immunophenotyping of Diverse Mouse Strains. ASM Journals Vol. 13, No. 1. doi.org/10.1128/mbio.03400-21.
- Seim GL, Britt EC, John SV, Yeo FJ, Johnson AR, Eisenstein RS, Pagliarini DJ & Fan J. Two-stage metabolic remodelling in macrophages in response to lipopolysaccharide and interferon-γ stimulation. Nature. 2019, July 12. doi.org/10.1038/s42255-019-0083-2.
- Mergaert AM, Denny MF, Kingstad-Bakke B, Bawadekar M, Bashar SJ, Warner TF, Suresh M,and Shelef MA. Peptidylarginine Deiminase 2 in Murine Antiviral and Autoimmune Antibody Responses. Journal of Immunology. Volume 2022, Jan 17. doi.org/10.1155/2022/5258221.
- Sonsalla MM, Lamming DW. Geroprotective interventions in the 3xTg mouse model of Alzheimer’s disease. Geroscience. 2023 Apr 6. doi: 10.1007/s11357-023-00782-w. PMID: 37022634.