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Mission
Our mission is to drive translational drug discovery and development through the design and synthesis of novel small molecule based therapeutics.
Contact
- Website Link
- Email: weiping.tang@wisc.edu
- Phone:(608) 890-1846
Facilities
- Facility Statement
Word PDF - Link to Equipment
- Line Diagram
- Link to UWCCC Acknowledging the Shared Resources Page
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Publications
- Xie H, Li C, Tang H, Tandon I, Liao J, Roberts BL, Zhao Y, Tang W. Development of Substituted Phenyl Dihydrouracil as the Novel Achiral Cereblon Ligands for Targeted Protein Degradation. J Med Chem. 2023 Feb 23;66(4):2904-2917. doi: 10.1021/acs.jmedchem.2c01941. Epub 2023 Feb 7. PMID: 36749666.
- Stevens CM, Zhou Y, Teng P, Rault LN, Liao Y, Tang W. Development of Oligomeric Mannose-6-phosphonate Conjugates for Targeted Protein Degradation. ACS Medicinal Chemistry Letters Article ASAP. doi: 10.1021/acsmedchemlett.2c00479
- Guo L, Liu J, Nie X, Wang T, Ma ZX, Yin D, Tang W. Development of selective FGFR1 degraders using a Rapid synthesis of proteolysis targeting Chimera (Rapid-TAC) platform. Bioorg Med Chem Lett. 2022 Nov 1;75:128982. doi: 10.1016/j.bmcl.2022.128982. Epub 2022 Sep 9. PMID: 36096343.