UW Vision Research Core

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Mission

The UW-Madison Vision Research Core is funded by the National Eye Institute (NEI), and provides vision researchers three distinct service areas: 1) Omics and quantitative molecular biology, 2) pathology & imaging, 3) animal models & eye organ culture.  We are also able to assist non-vision researchers who would like to utilize our instruments.

Contact

  • Website Link
  • Email:
    visioncore@ophth.wisc.edu
  • Telephone: 608-265-2572

Facilities

  • Facility Statement
    Word        PDF
  • Line Diagram

Rigor and Reproducibility

  • R&R Statement
    Word        PDF

Letter of Support

  • Letter of Support Template
    Word        PDF

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Publications

  1. Wurl JA, Mac Nair CE, Dietz JA, Shestopalov VI, Nickells RW. Contralateral Astrocyte Response to Acute Optic Nerve Damage Is Mitigated by PANX1 Channel Activity. Int J Mol Sci. 2023 Oct 27;24(21):15641. doi: 10.3390/ijms242115641. PMID: 37958624; PMCID: PMC10647301.
  2. Kabra M, Shahi PK, Wang Y, Sinha D, Spillane A, Newby GA, Saxena S, Tong Y, Chang Y, Abdeen AA, Edwards KL, Theisen CO, Liu DR, Gamm DM, Gong S, Saha K, Pattnaik BR. Nonviral base editing of KCNJ13 mutation preserves vision in a model of inherited retinal channelopathy. J Clin Invest. 2023 Oct 2;133(19):e171356. doi: 10.1172/JCI171356. PMID: 37561581; PMCID: PMC10541187.
  3. Wisner SR, Saha A, Grimes WN, Mizerska K, Kolarik HJ, Wallin J, Diamond JS, Sinha R, Hoon M. Sensory deprivation arrests cellular and synaptic development of the night-vision circuitry in the retina. Curr Biol. 2023 Oct 23;33(20):4415-4429.e3. doi: 10.1016/j.cub.2023.08.087. Epub 2023 Sep 27. PMID: 37769662; PMCID: PMC10615854.
  4. Sauter MM, Noel H, Brandt CR. The RLR intrinsic antiviral system is expressed in neural retina and restricts lentiviral transduction of human Mueller cells. Exp Eye Res. 2023 Nov;236:109647. doi: 10.1016/j.exer.2023.109647. Epub 2023 Sep 7. PMID: 37689341; PMCID: PMC10834037.