Small Animal Imaging and Radiotherapy Facility (SAIRF) ֍

This is a 3D image of one of the rooms in SAIRF.

Click on the picture above to take a 3D tour and learn more about the equipment for 4 of the rooms in SAIRF.

Contact

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Mission

The SAIRF is dedicated to providing innovative, state-of-the-art, affordable, noninvasive, high-resolution, in-vivo and ex-vivo imaging and radiotherapy support to UWCCC investigators, University of Wisconsin researchers, and industry.

Facilities

Rigor and Reproducibility

  • R&R Statement
    Word        PDF

Letter of Support

  • Letter of Support Template
    Word        PDF

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Publications

  1. Patel RB, Hernandez R, Carlson P, Grudzinski J, Bates AM, Jagodinsky JC, Erbe A, Marsh IR, Arthur I, Aluicio-Sarduy E, Sriramaneni RN, Jin WJ, Massey C, Rakhmilevich AL, Vail D, Engle JW, Le T,  Kim K, Bednarz B, Sondel PM, Weichert J, Morris ZS. Low-dose targeted radionuclide therapy renders immunologically cold tumors responsive to immune checkpoint blockade. Sci Transl Med. 2021 Jul 14;13(602):eabb3631. doi:10.1126/scitranslmed.abb3631. PMID: 34261797 PMCID: PMC8449934.
  2. Hernandez R, Graves SA, Gregg T, VanDeusen HR, Fenske RJ, Wienkes HN, England CG, Valdovinos HF, Jeffery JJ, Barnhart TE, Severin GW, Nickles RJ, Kimple ME, Merrins MJ, Cai W. Radiomanganese PET detects changes in functional β-cell mass in mouse models of diabetes. Diabetes. 2017 Aug;66(8):2163-2174. doi: 10.2337/db16-1285. PMID: 28515126 PMCID: PMC5521871.
  3. Yang Y, Hernandez R, Rao J, Yin L, Qu Y, Wu J, England CG, Graves SA, Lewis CM, Wang P, Meyerand ME, Nickles RJ, Bian XW, Cai W. Targeting CD146 with a 64Cu-labeled antibody enables in vivo immunoPET imaging of high-grade gliomas. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6525-34. doi:10.1073/pnas.1502648112. PMID: 26553993 PMCID: PMC4664343.
  4. Weichert JP, Clark PA, Kandela IK, Abram M, Clarke W, Longino MA, Pinchuk AN, Farhoud M, Swanson KI, Floberg JM, Grudzinski JJ, Titz B, Traynor AM, Chen H, Hall LT, Pazoles CJ, Pickhardt PJ, Kuo JS. Alkylphosphocholine analogs for broad spectrum cancer imaging and therapy. Sci Transl Med. 2014 Jun 11; 6(240): 240ra75. doi: 10.1126/scitranslmed.3007646. PMID: 24920661 PMCID: PMC4336181.
  5. Swanson KI, Clark PA, Zhang RR, Kandela, IK, Farhoud, M, Weichert, JP, Kuo, JS. Fluorescent Cancer-Selective Alkylphosphocholine Analogs for Intraoperative Glioma Detection. Neurosurgery. 2015 Feb; 76(2): 115–124. doi:10.1227/NEU.0000000000000622. PMID: 25549194 PMCID: PMC4343207.

Link to All SAIRF Pubs

֍ This core facility utilizes iLab, an online management tool that allows researchers to request services, schedule equipment and manage billing with UW shared resources.