Experimental Animal Pathology Core (EAPL)֍

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Mission

We provide a comprehensive array of histopathology services and expertise that allows researchers to fully exploit the power of animal models to reveal mechanisms that contribute to disease processes.

Contact

Rigor and Reproducibility

  • R&R Statement
    Word        PDF

Letter of Support

  • Letter of Support Template
    Word        PDF

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Publications

  1. Kim EJ, Liu P, Zhang S, Donahue K, Wang Y, Schehr JL, Wolfe SK, Dickerson A, Lu L, Rui L, Zhong X, Wisinski KB, Yu M, Suzuki A, Lang JM, Ong IM, Xu W. BAF155 methylation drives metastasis by hijacking super-enhancers and subverting anti-tumor immunity. Nucleic Acids Res. 2021 Dec 2;49(21):12211-12233. doi: 10.1093/nar/gkab1122. PMID: 34865122; PMCID: PMC8643633.
  2. Carr RM, Vorobyev D, Lasho T, Marks DL, Tolosa EJ, Vedder A, Almada LL, Yurcheko A, Padioleau I, Alver B, Coltro G, Binder M, Safgren SL, Horn I, You X, Solary E, Balasis ME, Berger K, Hiebert J, Witzig T, Buradkar A, Graf T, Valent P, Mangaonkar AA, Robertson KD, Howard MT, Kaufmann SH, Pin C, Fernandez-Zapico ME, Geissler K, Droin N, Padron E, Zhang J, Nikolaev S, Patnaik MM. RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis. Nat Commun. 2021 May 18;12(1):2901. doi: 10.1038/s41467-021-23186-w. PMID: 34006870; PMCID: PMC8131698.
  3. Pasch CA, Favreau PF, Yueh AE, Babiarz CP, Gillette AA, Sharick JT, Karim MR, Nickel KP, DeZeeuw AK, Sprackling CM, Emmerich PB, DeStefanis RA, Pitera RT, Payne SN, Korkos DP, Clipson L, Walsh CM, Miller D, Carchman EH, Burkard ME, Lemmon KK, Matkowskyj KA, Newton MA, Ong IM, Bassetti MF, Kimple RJ, Skala MC, Deming DA. Patient-Derived Cancer Organoid Cultures to Predict Sensitivity to Chemotherapy and Radiation. Clin Cancer Res. 2019 Sep 1;25(17):5376-5387. doi: 10.1158/1078-0432.CCR-18-3590. Epub 2019 Jun 7. PMID: 31175091; PMCID: PMC6726566.

 

Note:  EAPL maintains a list of select publications that utilized EAPL services on their webpage at: https://cancer.wisc.edu/research/resources/tsb/epl/select-scientific-accomplishments

֍ This core facility utilizes iLab, an online management tool that allows researchers to request services, schedule equipment and manage billing with UW shared resources.