Cancer Pharmacology Laboratory (CPL)֍

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Mission

The mission of the Cancer Pharmacology Laboratory is to advance cancer research by providing expertise; leadership; and bioanalytical assay development, validation and performance in support of the clinical, translational and laboratory research endeavors of UWCCC investigators.

Contact

Rigor and Reproducibility

Letter of Support

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Publications

  1. Gunder LC, Johnson HR, Yao E, Moyer TH, Green HA, Sherer N, Zhang W, Carchman EH. Topical Protease Inhibitor Decreases Anal Carcinogenesis in a Transgenic Mouse Model of HPV Anal Disease. Viruses. 2023 Apr 20;15(4):1013. doi: 10.3390/v15041013. PMID: 37112993; PMCID: PMC10146494.
  2. Leal TA, Sharifi MN, Chan N, Wesolowski R, Turk AA, Bruce JY, O’Regan RM, Eickhoff J, Barroilhet LM, Malhotra J, Mehnert J, Girda E, Wiley E, Schmitz N, Andrews S, Liu G, Wisinski KB. A phase I study of talazoparib (BMN 673) combined with carboplatin and paclitaxel in patients with advanced solid tumors (NCI9782). Cancer Med. 2022 Nov;11(21):3969-3981. doi: 10.1002/cam4.4724. Epub 2022 Apr 8. PMID: 35396812; PMCID: PMC9636507.
  3. Gunder LC, Johnson HR, Green HA, Bilger A, Moyer TH, Zhang W, Ziolkowski MR, Bertrang PA, Carchman EH. The use of a topical protease inhibitor, Saquinavir, to alleviate mouse papillomavirus-mediated anal disease. Virology. 2022 Nov;576:96-104. doi: 10.1016/j.virol.2022.09.012. Epub 2022 Sep 29. PMID: 36206607.
  4. Scribano CM, Wan J, Esbona K, Tucker JB, Lasek A, Zhou AS, Zasadil LM, Molini R, Fitzgerald J, Lager AM, Laffin JJ, Correia-Staudt K, Wisinski KB, Tevaarwerk AJ, O’Regan R, McGregor SM, Fowler AM, Chappell RJ, Bugni TS, Burkard ME, Weaver BA. Chromosomal instability sensitizes patient breast tumors to multipolar divisions induced by paclitaxel. Sci Transl Med. 2021 Sep 8;13(610):eabd4811. doi: 10.1126/scitranslmed.abd4811. Epub 2021 Sep 8. PMID: 34516829; PMCID: PMC8612166.
  5. Jarrard D, Filon M, Huang W, Havighurst T, DeShong K, Kim K, Konety BR, Saltzstein D, Mukhtar H, Wollmer B, Suen C, House MG, Parnes HL, Bailey HH. A phase II randomized placebo-controlled trial of pomegranate fruit extract in men with localized prostate cancer undergoing active surveillance. Prostate. 2021 Jan;81(1):41-49. doi: 10.1002/pros.24076. Epub 2020 Oct 23. PMID: 33095939.

֍ This core facility utilizes iLab, an online management tool that allows researchers to request services, schedule equipment and manage billing with UW shared resources.